A Computational Model of Biophysical Properties of the Rat Stomach Informed by Comprehensive Analysis of Muscle Anatomy.

Abstract

An anatomically based 3D computational model of the rat stomach was developed using experimental muscle thickness measurements and muscle fiber orientations for the longitudinal muscle (LM) and circular muscle (CM) layers. First, 15 data points corresponding to the measurements were registered on the dorsal and ventral faces of the serosal surface of an averaged 3D rat stomach model. A thickness field representing the varying wall thickness was fitted to the surface and nodal points were projected outwards (for the LM layer) and inwards (for the CM layer) to create 2 new surfaces. In addition, a computational volume mesh was created and fiber orientation in each tetrahedral element was compu..